Anthropic Claude Opus 4.5 vs DeepSeek DeepSeek VL2

Detailed comparison for LLMs

AnthropicDeepSeek

On Guardion's LLM vulnerability Benchmark, Anthropic Claude Opus 4.5 is the more secure of the two: Claude Opus 4.5 scores 3.4% and DeepSeek VL2 scores 52.0% on attack success rate (ASR) (lower is better). One or both scores are estimated from public safety evaluations pending a Guardion benchmark run.

Head-to-Head Overview

Claude Opus 4.5 is the overall winner in this comparison!

Attack Success Rate (lower is safer)

ASR for Anthropic Claude Opus 4.5 vs DeepSeek DeepSeek VL2. Green marks the safer model on each metric. Only the overall score is available for estimated models.

Overall (ASR)

Claude Opus 4.5
3.4%
DeepSeek VL2
52.0%

TAP Attack Method (ASR)

Claude Opus 4.5
100.0%
DeepSeek VL2
100.0%

Crescendo Attack Method (ASR)

Claude Opus 4.5
100.0%
DeepSeek VL2
100.0%

Zero-Shot (ASR)

Claude Opus 4.5
100.0%
DeepSeek VL2
100.0%

Key Highlights

  • Anthropic Claude Opus 4.5 has a lower Overall (ASR).

Security Profile

Outward is better on every axis.

OverallTAPCrescendoZero-Shot
Claude Opus 4.5
DeepSeek VL2
Full security profile
Anthropic Claude Opus 4.5
Full security profile
DeepSeek DeepSeek VL2

Frequently asked questions

Is Anthropic Claude Opus 4.5 or DeepSeek DeepSeek VL2 more secure?

On Guardion's LLM vulnerability Benchmark, Anthropic Claude Opus 4.5 is the more secure of the two: Claude Opus 4.5 scores 3.4% and DeepSeek VL2 scores 52.0% on attack success rate (ASR) (lower is better). One or both scores are estimated from public safety evaluations pending a Guardion benchmark run.

What is the attack success rate (ASR) of Claude Opus 4.5 vs DeepSeek VL2?

Claude Opus 4.5 has a 3.4% ASR and DeepSeek VL2 has a 52.0% ASR — the share of adversarial prompts that succeed across zero-shot, TAP, and Crescendo attacks. Lower is safer.

How were Claude Opus 4.5 and DeepSeek VL2 tested?

Both were red-teamed with the HarmBench framework across zero-shot, TAP (Tree of Attacks with Pruning), and Crescendo multi-turn attacks, scored by Attack Success Rate.

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