Anthropic Claude Opus 4.5 vs Deepseek Deepseek V3

Detailed comparison for LLMs

AnthropicDeepseek

On Guardion's LLM vulnerability Benchmark, Anthropic Claude Opus 4.5 is the more secure of the two: Claude Opus 4.5 scores 3.4% and Deepseek V3 scores 47.2% on attack success rate (ASR) (lower is better). One or both scores are estimated from public safety evaluations pending a Guardion benchmark run.

Head-to-Head Overview

Claude Opus 4.5 is the overall winner in this comparison!

Attack Success Rate (lower is safer)

ASR for Anthropic Claude Opus 4.5 vs Deepseek Deepseek V3. Green marks the safer model on each metric. Only the overall score is available for estimated models.

Overall (ASR)

Claude Opus 4.5
3.4%
Deepseek V3
47.2%

TAP Attack Method (ASR)

Claude Opus 4.5
100.0%
Deepseek V3
79.5%

Crescendo Attack Method (ASR)

Claude Opus 4.5
100.0%
Deepseek V3
49.3%

Zero-Shot (ASR)

Claude Opus 4.5
100.0%
Deepseek V3
12.8%

Key Highlights

  • Anthropic Claude Opus 4.5 has a lower Overall (ASR).
  • Deepseek Deepseek V3 has a lower TAP Attack Method (ASR).
  • Deepseek Deepseek V3 has a lower Crescendo Attack Method (ASR).
  • Deepseek Deepseek V3 has a lower Zero-Shot (ASR).

Security Profile

Outward is better on every axis.

OverallTAPCrescendoZero-Shot
Claude Opus 4.5
Deepseek V3
Full security profile
Anthropic Claude Opus 4.5
Full security profile
Deepseek Deepseek V3

Frequently asked questions

Is Anthropic Claude Opus 4.5 or Deepseek Deepseek V3 more secure?

On Guardion's LLM vulnerability Benchmark, Anthropic Claude Opus 4.5 is the more secure of the two: Claude Opus 4.5 scores 3.4% and Deepseek V3 scores 47.2% on attack success rate (ASR) (lower is better). One or both scores are estimated from public safety evaluations pending a Guardion benchmark run.

What is the attack success rate (ASR) of Claude Opus 4.5 vs Deepseek V3?

Claude Opus 4.5 has a 3.4% ASR and Deepseek V3 has a 47.2% ASR — the share of adversarial prompts that succeed across zero-shot, TAP, and Crescendo attacks. Lower is safer.

How were Claude Opus 4.5 and Deepseek V3 tested?

Both were red-teamed with the HarmBench framework across zero-shot, TAP (Tree of Attacks with Pruning), and Crescendo multi-turn attacks, scored by Attack Success Rate.

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