Anthropic Claude Opus 4.5 vs Deepseek Deepseek R1

Detailed comparison for LLMs

AnthropicDeepseek

On Guardion's LLM vulnerability Benchmark, Anthropic Claude Opus 4.5 is the more secure of the two: Claude Opus 4.5 scores 3.4% and Deepseek R1 scores 42.6% on attack success rate (ASR) (lower is better). One or both scores are estimated from public safety evaluations pending a Guardion benchmark run.

Head-to-Head Overview

Claude Opus 4.5 is the overall winner in this comparison!

Attack Success Rate (lower is safer)

ASR for Anthropic Claude Opus 4.5 vs Deepseek Deepseek R1. Green marks the safer model on each metric. Only the overall score is available for estimated models.

Overall (ASR)

Claude Opus 4.5
3.4%
Deepseek R1
42.6%

TAP Attack Method (ASR)

Claude Opus 4.5
100.0%
Deepseek R1
76.9%

Crescendo Attack Method (ASR)

Claude Opus 4.5
100.0%
Deepseek R1
34.8%

Zero-Shot (ASR)

Claude Opus 4.5
100.0%
Deepseek R1
16.1%

Key Highlights

  • Anthropic Claude Opus 4.5 has a lower Overall (ASR).
  • Deepseek Deepseek R1 has a lower TAP Attack Method (ASR).
  • Deepseek Deepseek R1 has a lower Crescendo Attack Method (ASR).
  • Deepseek Deepseek R1 has a lower Zero-Shot (ASR).

Security Profile

Outward is better on every axis.

OverallTAPCrescendoZero-Shot
Claude Opus 4.5
Deepseek R1
Full security profile
Anthropic Claude Opus 4.5
Full security profile
Deepseek Deepseek R1

Frequently asked questions

Is Anthropic Claude Opus 4.5 or Deepseek Deepseek R1 more secure?

On Guardion's LLM vulnerability Benchmark, Anthropic Claude Opus 4.5 is the more secure of the two: Claude Opus 4.5 scores 3.4% and Deepseek R1 scores 42.6% on attack success rate (ASR) (lower is better). One or both scores are estimated from public safety evaluations pending a Guardion benchmark run.

What is the attack success rate (ASR) of Claude Opus 4.5 vs Deepseek R1?

Claude Opus 4.5 has a 3.4% ASR and Deepseek R1 has a 42.6% ASR — the share of adversarial prompts that succeed across zero-shot, TAP, and Crescendo attacks. Lower is safer.

How were Claude Opus 4.5 and Deepseek R1 tested?

Both were red-teamed with the HarmBench framework across zero-shot, TAP (Tree of Attacks with Pruning), and Crescendo multi-turn attacks, scored by Attack Success Rate.

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