Alibaba Qwen 2.5 72B vs Anthropic Claude Opus 4.5

Detailed comparison for LLMs

AlibabaAnthropic

On Guardion's LLM vulnerability Benchmark, Anthropic Claude Opus 4.5 is the more secure of the two: Qwen 2.5 72B scores 26.3% and Claude Opus 4.5 scores 3.4% on attack success rate (ASR) (lower is better). One or both scores are estimated from public safety evaluations pending a Guardion benchmark run.

Head-to-Head Overview

Claude Opus 4.5 is the overall winner in this comparison!

Attack Success Rate (lower is safer)

ASR for Alibaba Qwen 2.5 72B vs Anthropic Claude Opus 4.5. Green marks the safer model on each metric. Only the overall score is available for estimated models.

Overall (ASR)

Qwen 2.5 72B
26.3%
Claude Opus 4.5
3.4%

TAP Attack Method (ASR)

Qwen 2.5 72B
55.2%
Claude Opus 4.5
100.0%

Crescendo Attack Method (ASR)

Qwen 2.5 72B
23.7%
Claude Opus 4.5
100.0%

Zero-Shot (ASR)

Qwen 2.5 72B
0.3%
Claude Opus 4.5
100.0%

Key Highlights

  • Anthropic Claude Opus 4.5 has a lower Overall (ASR).
  • Alibaba Qwen 2.5 72B has a lower TAP Attack Method (ASR).
  • Alibaba Qwen 2.5 72B has a lower Crescendo Attack Method (ASR).
  • Alibaba Qwen 2.5 72B has a lower Zero-Shot (ASR).

Security Profile

Outward is better on every axis.

OverallTAPCrescendoZero-Shot
Qwen 2.5 72B
Claude Opus 4.5
Full security profile
Alibaba Qwen 2.5 72B
Full security profile
Anthropic Claude Opus 4.5

Frequently asked questions

Is Alibaba Qwen 2.5 72B or Anthropic Claude Opus 4.5 more secure?

On Guardion's LLM vulnerability Benchmark, Anthropic Claude Opus 4.5 is the more secure of the two: Qwen 2.5 72B scores 26.3% and Claude Opus 4.5 scores 3.4% on attack success rate (ASR) (lower is better). One or both scores are estimated from public safety evaluations pending a Guardion benchmark run.

What is the attack success rate (ASR) of Qwen 2.5 72B vs Claude Opus 4.5?

Qwen 2.5 72B has a 26.3% ASR and Claude Opus 4.5 has a 3.4% ASR — the share of adversarial prompts that succeed across zero-shot, TAP, and Crescendo attacks. Lower is safer.

How were Qwen 2.5 72B and Claude Opus 4.5 tested?

Both were red-teamed with the HarmBench framework across zero-shot, TAP (Tree of Attacks with Pruning), and Crescendo multi-turn attacks, scored by Attack Success Rate.

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